Blar i forfatter "Sonnenberg, Cecilie Bækkedal"

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    • Bipartite Genomes in Enterobacterales: Independent Origins of Chromids, Elevated Openness and Donors of Horizontally Transferred Genes 

      Sonnenberg, Cecilie Bækkedal; Haugen, Peik (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-21)
      Multipartite bacteria have one chromosome and one or more chromid. Chromids are believed to have properties that enhance genomic flexibility, making them a favored integration site for new genes. However, the mechanism by which chromosomes and chromids jointly contribute to this flexibility is not clear. To shed light on this, we analyzed the openness of chromosomes and chromids of the two bacteria, ...

    • Exploring multipartite genomes using pangenome analysis 

      Sonnenberg, Cecilie Bækkedal (Doctoral thesis; Doktorgradsavhandling, 2023-06-21)
      <p>Bacteria are small single-celled organisms that are found in nearly every habitat on Earth. While bacterial genomes usually consist of one large circular replicon, about 10% of bacteria have organized their genes onto several large replicons. These multipartite bacteria are often found in symbiotic or pathogenic relationships with other higher organisms and are believed to have greater ability ...

    • The Pseudoalteromonas multipartite genome: distribution and expression of pangene categories, and a hypothesis for the origin and evolution of the chromid 

      Sonnenberg, Cecilie Bækkedal; Haugen, Peik (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-21)
      Bacterial genomes typically consist of one large chromosome, but can also include secondary replicons. These so-called multipartite genomes are scattered on the bacterial tree of life with the majority of cases belonging to Proteobacteria. Within the class gamma-proteobacteria, multipartite genomes are restricted to the two families <i>Vibrionaceae</i> and <i>Pseudoalteromonadaceae</i>. Whereas the ...

    • Vibrionaceae core, shell and cloud genes are non-randomly distributed on Chr 1: An hypothesis that links the genomic location of genes with their intracellular placement 

      Sonnenberg, Cecilie Bækkedal; Kahlke, Tim; Haugen, Peik (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-06)
      <i>Background</i> - The genome of <i>Vibrionaceae</i> bacteria, which consists of two circular chromosomes, is replicated in a highly ordered fashion. In fast-growing bacteria, multifork replication results in higher gene copy numbers and increased expression of genes located close to the origin of replication of Chr 1 (<i>ori1</i>). This is believed to be a growth optimization strategy to satisfy ...